In rehabilitation centers located in Boston (MA), Chicago, (IL), and Providence, (RI), Cyberkinetics Neurotechnology Systems, Inc has initiated a pilot study evaluating the potential of their BrainGate^TM device to translate movement-related thoughts into environment-controlling actions in individuals with high-level injuries. About 4 mm in size (~ the size of a baby aspirin), the device is composed of an array of hair-size electrodes and implanted in the brain area responsible for movement. This device transmits thought-stimulated, movement-associated neuronal signals through the skull to a computer for analysis and processing. This, in turn, is translated into user-controlled actions mediated through electronic devices, such a computer cursor, a remote control, limb-controlling neural prostheses, etc. Although the overall concept of thought-controlled movement is not new, with ever-growing technical sophistication over time, the development of real-world applications is becoming an increasing reality. 1